Specific oral microbial signatures carried a 9.5-fold odds ratio for esophageal squamous cell carcinoma — one of the strongest statistical links in the literature.
Sets a precedent for microbiome-based risk prediction with statistical rigour.
The studies Orvana's risk readouts build on. All peer-reviewed, each chosen because it shows the oral microbiome doing real predictive work — not because it sounds good in a deck.
Distinct oral microbial signatures carried a 9.5-fold odds ratio for esophageal squamous cell carcinoma — among the strongest statistical links in the field.
From cancer-risk prediction to saliva as a biomarker — the evidence base supporting risk stratification from an oral sample.
Specific oral microbial signatures carried a 9.5-fold odds ratio for esophageal squamous cell carcinoma — one of the strongest statistical links in the literature.
Sets a precedent for microbiome-based risk prediction with statistical rigour.
Probiotics and oral-hygiene interventions shift the oral microbiome and reduce downstream disease risk.
Supports Orvana's preventive positioning and gives users actionable levers.
Changes in oral microbial communities track cardiometabolic risk factors and systemic inflammation.
Maps clear mechanistic links between oral dysbiosis and heart/metabolic disease risk.
Salivary microbial profiling is a validated, non-invasive source for monitoring diabetes, cardiovascular and neurodegenerative conditions.
Justifies Orvana's at-home saliva collection model and consumer workflow.
Every readout Orvana ships traces back to peer-reviewed work. We publish sources rather than asking you to take the science on trust — and we update this list as the evidence moves.